Photocontrol of Contracting Muscle Fibers

C. Hoppmann*; P. Schmieder; P. Domaing; G. Vogelreiter; J. Eichhorst; B. Wiesner; I. Morano; K. Rück-Braun K; M. Beyermann;

Angew. Chem. Int. Ed. 50, 7841–7845 (2011)

A twitch in time: Light-directed inhibition of the interaction between a-1-syntrophin and neuronal NO synthase (nNOS) in living skeletal muscle with a cell-permeable photoswitchable nNOS-derived peptide ligand results in photocontrol of muscle performance and nitric oxide signaling.

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